Johnny's tired of the toys found in cereal boxes, so he launches his own 'Johnny Os' with a real alien blaster found in each box. Dukey's starting to behave too much like a regular dog. It's time for a DNA upgrade.
Time and space collide when a machine able to harness time travel is taken over by MAD, and Talon starts to replay the same day over and over and over. Then, Chief Quimby wants Gadget to go on vacation, but Gadget thinks he's being sent on a mission.
Following an insect mishap, Clarence's house needs to be fumigated, forcing Mary, Chad, and Clarence into a motel. While there, Clarence and Chad learn a bit about responsibility, while Mary contemplates a life of letting go.
McCool takes the Falcones to Cuba on vacation. Jimmy hates it for being a 'Communist hell-hole,' but cheers up when he discovers that killing Castro can get him 'Super-Made' and land him back on top in New York.