Follow the hectic life of Jackie Peyton, a nurse in the emergency ward of All Saints' Hospital in New York City. Jackie works with her best friend Dr. Eleanor O'Hara, the inexperienced but excited student nurse Zoey and the talented golden boy Dr. Cooper. While handling patients and assisting doctors, she tries to settle her personal life with her husband and daughters while hiding her own battle with using pain medication like Vicodin and Oxycontin to help her get through the long days.
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