Death row guards at a penitentiary form an unusual relationship with an inmate who seems to possess extraordinary powers. They are faced with a moral dilemma when they come to believe the inmate may actually be innocent.
A serial killer is on the loose. At their wits ends, the FBI enlists new recruit Clarice and the help of a psychotic genius who is behind bars. In order to stop a madman, Clarice must overcome her aversion to her disturbing new partner.
Tulip makes her way to Cassidy and Eugene catches up with his Preacher, though this reunion might be cut short by the Saint of Killers. Starr struggles to keep track of the many players of the apocalypse as the Grail's agenda threatens to unwind.
Starr is desperately searching for the messiah as the clock ticks down to apocalypse. Tulip and Cass assume fake identities to track Jesse, but the Saint of Killers has him on a short leash, leading him straight towards an explosive end.
Tulip and Cassidy tear across the world, hell-bent on making God pay for the latest bloody twist in His plan. Elsewhere, an old friend presents Jesse with a unique opportunity that could change everything.